Chondrocytes on the epiphyseal side of the epiphyseal plate divide; one cell remains undifferentiated near the epiphysis, and one cell moves toward the diaphysis. The cells, which are pushed from the epiphysis, mature and are destroyed by calcification. This process replaces cartilage with bone on the diaphyseal side of the plate, resulting in a lengthening of the bone. Long bones stop growing at around the age of 18 in females and the age of 21 in males in a process called epiphyseal plate closure.
During this process, cartilage cells stop dividing and all of the cartilage is replaced by bone. The epiphyseal plate fades, leaving a structure called the epiphyseal line or epiphyseal remnant, and the epiphysis and diaphysis fuse. Appositional growth is the increase in the diameter of bones by the addition of bony tissue at the surface of bones.
Osteoblasts at the bone surface secrete bone matrix, and osteoclasts on the inner surface break down bone. The osteoblasts differentiate into osteocytes. A balance between these two processes allows the bone to thicken without becoming too heavy. Bone renewal continues after birth into adulthood. Bone remodeling is the replacement of old bone tissue by new bone tissue. It involves the processes of bone deposition by osteoblasts and bone resorption by osteoclasts.
Normal bone growth requires vitamins D, C, and A, plus minerals such as calcium, phosphorous, and magnesium. Hormones such as parathyroid hormone, growth hormone, and calcitonin are also required for proper bone growth and maintenance.
Bone turnover rates are quite high, with five to seven percent of bone mass being recycled every week. Differences in turnover rate exist in different areas of the skeleton and in different areas of a bone.
For example, the bone in the head of the femur may be fully replaced every six months, whereas the bone along the shaft is altered much more slowly. Figure 2. After this bone is set, a callus will knit the two ends together.
Deepa Saini. Jasmine Chudhary. Vinoth Prabhhu. P Hospital. Madhavee Madhavee. Mohmed Mohmedy. Mwakyoma Bahati. Show More. Views Total views. Actions Shares. No notes for slide. Post traumatic myocitis ossificans. Small vessels calcification DM,Hyperparthyroidism. India,Africa,Middle East This may be so extensive that layering of the calcium is seen.
With treatment of hypercalcemia the soft tissue calcification may resolves. It usually forms in the periphery of the hematoma ,at this stage an isotope bone scan will show increased uptake. This slowly absorbs and disappears with time although an irregular bone density may persists for years. Calcification with soft tissues necrosis. Post traumatic fat necrosis results in coarse spheroid calcified masses.
Normally in breast diseases like in-situ ductal carcinoma, calcium is deposited at sites of cell death. Calcification can be diagnosed through ultrasound or radiography. Ossification or osteogenesis is the formation of bones from osteoblast cells. Ossification is different from calcification.
Ossification takes place approximately six weeks after fertilization in an embryo. It is mainly classified into two types: intramembranous ossification and endochondral ossification. The intramembranous ossification forms the flat bones of the skull, mandible and hip bone. Intramembranous ossification is an essential process during the natural healing process of bone fractures and the rudimentary formation of bones of the skull.
In intramembranous ossification, bone is developed from fibrous tissue. Endochondral ossification , on the other hand, is an extremely important process during the rudimentary formation of long bones. It helps the growth of the length of the bones and natural healing of the bone fractures. In endochondral ossification, the bone is developed from hyaline cartilage.
Calcification is the process in which calcium salts build up in tissues, while ossification is the process of laying down new bone material or formation of new bone tissue. Accessed 11 Nov. More Definitions for calcify. Britannica English: Translation of calcify for Arabic Speakers.
Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! Log in Sign Up. Save Word. Definition of calcify. Other Words from calcify What is the difference between ossify and calcify? Example Sentences Learn More About calcify. What is the difference between ossify and calcify? Calcify refers to hardening, to becoming inflexible and unable to change: What were once upstart revisionist currents calcified into self-regarding academic sub-specialties, sponsoring plenty of analysis but little fundamental debate.
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